Table 3.
Univariate and multivariate analysis in patients with esophageal cancer.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age at diagnosis | ||||||
| >60 vs. ≤60 | 0.931 | 0.576–1.506 | 0.771 | 0.933 | 0.567–1.534 | 0.783 |
| Pathologic stage | ||||||
| III + IV vs. I + II | 2.065 | 1.530–2.786 | <0.001 | 1.995 | 1.299–3.064 | 0.002 |
| T Stage | ||||||
| T3 + T4 vs. T1 + T2 | 1.474 | 1.055–2.060 | 0.023 | 1.144 | 0.813–1.611 | 0.440 |
| Lymph node status | ||||||
| N1-2 vs. N0 | 1.395 | 1.120–1.738 | 0.003 | 1.048 | 0.805–1.365 | 0.726 |
| Distant metastasis | ||||||
| M1 vs. M0 | 2.163 | 1.250–3.743 | 0.006 | 1.022 | 0.508–2.057 | 0.951 |
| Three-miRNA signature | ||||||
| high-risk vs. low-risk | 3.234 | 1.457–7.174 | 0.004 | 3.442 | 1.475–8.035 | 0.004 |
HR, hazard ratio; 95% CI, 95% confidence interval; vs., versus.