Table 3.
Linear regression evaluating the association of MetS components with traditional diabetic complications and mild cognitive impairment
| Variable | NIH Toolbox composite^† | E-to-I ratio | Mean deviation | ACR** |
|---|---|---|---|---|
| Age | −0.004 (−0.01, −0.002)* | 0.06 (−0.005, 0.13) | −0.02 (−0.05, 0.01) | |
| Female (reference male) | 8.49 (−1.84, 18.82) | 0.02 (−0.04, 0.08) | 0.96 (−1.27, 3.19) | −0.56 (−1.69, 0.57) |
| Height (unit = 5 cm) | 0.23 (−0.23, 0.68) | −0.001 (−0.01, 0.01) | 0.29 (−0.18, 0.75) | −0.10 (−0.34, 0.14) |
| Glycemic status | ||||
| Prediabetes (reference normal) | −2.58 (−10.57, 5.40) | −0.01 (−0.06, 0.03) | −1.78 (−3.56, −0.002)* | 0.54 (−0.37, 1.45) |
| Diabetes (reference normal) | −3.49 (−12.31, 5.34) | −0.03 (−0.09, 0.02) | −1.42 (−3.39, 0.55) | 0.01 (−1.00, 1.02) |
| SBP (unit = 10 mmHg) | 2.30 (0.12, 4.48)* | 0.004 (−0.01, 0.02) | −0.24 (−0.72, 0.24) | −0.03 (−0.27, 0.21) |
| Triglycerides (unit = 50 mg/dL) | −1.02 (−2.80, 0.76) | −0.01 (−0.02, 0.003) | 0.13 (−0.27, 0.53) | 0.21 (0.01, 0.41)* |
| HDL (unit = 10 mg/dL) | −3.38 (−6.38, −0.37)* | −0.01 (−0.02, 0.01) | 0.09 (−0.58, 0.75) | −0.02 (−0.36, 0.31) |
| Waist circumference (unit = 5 cm) | −1.48 (−2.38, −0.57)* | −0.01 (−0.01, −0.002)* | −0.02 (−0.21, 0.18) | 0.04 (−0.06, 0.14) |
Data are presented with the 95% CI. SBP, systolic blood pressure. *P < 0.01.
^
Adjusted for age, WRAT4, and education level.
†
Used Multiple Imputation using Chained Equations (MICE) with predictive mean matching and 50 imputations. Effect estimates are pooled using Rubin’s rules.
**
Log-transformed (ACR + 1).