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. Author manuscript; available in PMC: 2020 Feb 22.
Published in final edited form as: Lancet. 2016 Jun 17;388(10042):412–436. doi: 10.1016/S0140-6736(16)00684-X

Table II.

Methodological Overview of Transgender Health Study Designs as Reported by Study Authors (n=116 studies).

Column A Column B Column C

Study Design # Studies Sampling Method # Studies Measures of Association # Studies
Cross-sectional 90 Clinic-based recruitment (gender dysphoric participants) and internet-based recruitment (controls) 29 Prevalence 95
Prospective cohort 7 Internet-based or online recruitment 17 Age-standardized prevalence 1
Repeated cross sectional survey 2 Approached through trans organizations, referrals from venues, and internet advertisements 6 RDS-weighted prevalence 3
Pre post intervention design 2 Probability-based sampling 3 Standardized Mortality Ratio (SMR) 1
Randomized controlled efficacy trial 1 Respondent-driven sampling 8 Period prevalence (per 100,000 patients) 3
Retrospective chart review, case review, case series, case records 11 Recruitment from transgender events and conferences, or LGBT events including Pride Festivals 7 Incidence rate 4
Retrospective cohort 2 Not Specified 4 Cases/1000 persons 1
Case-control 1 Purposive community sampling 4 Risk ratio 1
Recruited from HIV-prevention program or outreach 3 Odds ratio 7
Convenience sample 2 Adjusted Odds Ratio 16
Peer outreach and snowball sampling 2 Unadjusted conditional odds 1
Venue-based sampling 2 Adjusted conditional odds 1
Snowball sampling 2 Hazard ratio 2
Snowball sampling and quota sampling 1 Beta (regression coefficient) 7
Snowball sampling, listservs, and websites 1 Point-biserial correlations 1
Brief-intercept sampling 1 Contrast estimate 1
Recruitment letter to students 1 Median 1
Organization-based recruitment 1 Mean score 4
Clinic-based, venue-based, peer outreach and referral 1 Chi square 2
Random sample from prison census 1 t-test 2
Random sample of selected gurus with all associated hijiras 1 MANOVA 1
Clinic service case records 2 Pearson’s correlation 1
HIV/STD Surveillance Registries 1
Clinic and location-based recruitment 1
School-based 1
Randomly selected high-schools 1
Venue-day-time sampling 1
Census 1
Clinic-based recruitment and peer referral 1
Community agency-based recruitment 1
Peer referral 2
Snowball/chain referral and venue based 1
Argentine Union of Sexual Workers registration 1
Community and internet-based 1
GSA organization-based recruitment 1
Venue-based sampling and incentivized snowball sampling 1
Consecutive clinic referral 1
Internet and peer referral 1