Fig. 5.
The anxiogenic effects of SKF 83959 are correlated with low-frequency oscillations in NAc. a Correlation curves showing a significant linear correlation between NAc theta oscillatory power with open arm time in female rats following 0.1 mg/kg and 0.25 mg/kg SKF 83959. b Correlation curves showing the relationship between NAc theta oscillatory power with open arm time in male rats following 0.1 and 0.25 mg/kg SKF 83959. A significant correlation was observed only at 0.25 mg/kg dose. c Correlation curves showing NAc delta oscillatory power with open arm time in female rats following 0.1 and 0.25 mg/kg SKF 83959. NAc delta oscillatory power correlated with open arm time in female rats selectively following 0.1 mg/kg SKF 83959. d Correlation curves showing the relationship between NAc delta oscillatory power with open arm time in male rats following 0.1 and 0.25 mg/kg SKF 83959. NAc delta oscillatory power correlated with open arm time in male rats selectively following 0.25 mg/kg SKF 83959. Points represent values taken from individual electrodes with line of best fit shown. N = 5–6/group with two electrodes/rat