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. 2020 Feb 21;22:33. doi: 10.1186/s13075-020-2131-4

Table 2.

Diagnostic values of the criteria and non-criteria aPLs

Parameters Sen Spe PPV NPV PLR NLR OR (95% CI) Youden index
LAC 0.4716 0.9808 0.9568 0.6732 24.6034 0.5387 45.67 (19.7–105.9) 1.4524
aCL IgA 0.3227 0.9617 0.8835 0.6118 8.417 0.7043 11.95 (6.37–22.41) 1.2844
aCL IgG 0.5993 0.9425 0.9037 0.723 10.421 0.4252 24.51 (14.4–41.73) 1.5418
aCL IgM 0.1525 0.9808 0.8776 0.5623 7.9545 0.8641 9.21 (3.85–21.99) 1.1333
aCL IgG/IgM 0.6277 0.9265 0.885 0.7342 8.5416 0.4019 21.25 (13.04–34.64) 1.5542
aCL IgA/G/M 0.6418 0.9105 0.866 0.7383 7.1749 0.3933 18.24 (11.54–28.84) 1.5523
aβ2GPI IgA 0.2979 0.9776 0.9231 0.6071 13.3191 0.7182 18.55 (8.4–40.92) 1.2755
aβ2GPI IgG 0.6702 0.9137 0.875 0.7546 7.7695 0.3609 21.53 (13.51–34.31) 1.5839
aβ2GPI IgM 0.1383 0.9776 0.8478 0.5574 6.1839 0.8814 7.02 (3.08–15.96) 1.1159
aβ2GPI D1 0.489 0.9712 0.9366 0.6862 17.0053 0.5262 32.32 (15.98–65.36) 1.4602
aβ2GPI IgG/M 0.6879 0.9073 0.87 0.7634 7.425 0.3439 21.59 (13.66–34.12) 1.5952
aΒ2GPI IgA/G/M 0.695 0.9073 0.8711 0.7676 7.5016 0.3361 22.32 (14.11–35.3) 1.6023
aΒ2GPI IgG/M/D1 0.6949 0.9042 0.863 0.7732 7.2496 0.3375 21.48 (13.61–33.9) 1.5991
aΒ2GPI IgA/G/M/D1 0.7022 0.9042 0.8643 0.7775 7.3263 0.3294 22.24 (14.08–35.14) 1.6064
aPSPT IgG 0.6213 0.9465 0.9135 0.7332 11.611 0.4001 29.02 (16.58–50.81) 1.5678
aPSPT IgM 0.636 0.8395 0.7828 0.7171 3.9619 0.4336 9.14 (6.15–13.57) 1.4755
aPSPT IgG/M 0.7978 0.8127 0.7949 0.8154 4.2597 0.2488 17.12 (11.31–25.92) 1.6105
aCL IgG/M/aΒ2GPI IgG/M/LAC 0.7872 0.8626 0.8377 0.8182 5.7303 0.2467 23.23 (15.11–35.71) 1.6498
aCL IgA/G/M/aΒ2GPI IgA/G/M/LAC 0.7943 0.8594 0.8358 0.8226 5.6505 0.2393 23.61 (15.36–36.3) 1.6537
aCL IgG/M/aΒ2GPI IgG/M/D1/LAC 0.7831 0.8594 0.8288 0.8201 5.5706 0.2524 22.07 (14.36–33.92) 1.6425
aPSPT IgG/M/aCL IgG/M/aΒ2GPI IgG/M/LAC 0.8897 0.7592 0.7707 0.8833 3.6948 0.1453 25.43 (16.01–40.4) 1.6489
aPSPT IgG/aCL IgA/aΒ2GPI IgA/G/LAC 0.8493 0.8763 0.8619 0.8647 6.863 0.172 39.9 (24.73–64.37) 1.7256
aPSPT IgG/aCL IgG/LAC 0.8235 0.8997 0.8819 0.8486 8.2078 0.1962 41.84 (25.65–68.26) 1.7232