Table 4.
Death of a child between ages 1 and 24 years in relation to the number of liveborn siblings preceding the birth of the current child
| Number of preceding liveborn siblings | Number of deaths (incidence rate per 100 000 person-years) |
HR (95% CI) | ||
| Unadjusted | Adjusted*† | |||
| Death due to any cause | 0 (n=1 542 071) | 3490 (16.5) | 1.00 (referent) | 1.00 (referent) |
| 1 (n=1 101 167) | 2353 (16.7) | 1.05 (1.00 to 1.11) | 1.16 (1.10 to 1.23) | |
| 2 (n=349 689) | 699 (17.5) | 1.17 (1.08 to 1.27) | 1.34 (1.23 to 1.45) | |
| 3+ (n=139 365) | 329 (23.9) | 1.68 (1.50 to 1.89) | 1.96 (1.74 to 2.21) | |
| Death due to non-injury | 0 (n=1 542 071) | 1727 (8.2) | 1.00 (referent) | 1.00 (referent) |
| 1 (n=1 101 167) | 1104 (7.8) | 0.95 (0.88 to 1.03) | 1.08 (1.00 to 1.17) | |
| 2 (n=349 689) | 339 (8.5) | 1.03 (0.91 to 1.15) | 1.22 (1.08 to 1.37) | |
| 3+ (n=139 365) | 151 (11.0) | 1.30 (1.10 to 1.54) | 1.62 (1.36 to 1.92) | |
| Death due to injury | 0 (n=1 542 071) | 1111 (5.3) | 1.00 (referent) | 1.00 (referent) |
| 1 (n=1 101 167) | 837 (5.9) | 1.20 (1.10 to 1.31) | 1.39 (1.27 to 1.52) | |
| 2 (n=349 689) | 219 (5.5) | 1.24 (1.07 to 1.43) | 1.60 (1.38 to 1.86) | |
| 3+ (n=139 365) | 105 (7.6) | 1.96 (1.59 to 2.42) | 2.77 (2.23 to 3.45) | |
Shown are deaths from any cause (upper), non-injury causes (middle) and injury causes (lower).
*Adjusted for maternal world region of origin, age at the child’s birth and the child’s year of birth, sex, preterm birth <37 weeks’ gestation, a congenital or chromosomal anomaly diagnosed before age 1 year and time-varying residential income quintile and rurality.
†7406 participants had missing information about the number of preceding liveborn siblings. Their corresponding adjusted HRs were 2.47 (95% CI 1.90 to 3.21) for death due to any cause, 3.70 (95% CI 2.73 to 5.02) for death due to non-injury and 1.50 (95% CI 0.81 to 2.78) for death due to injury.