Table 3.
Weaning outcome
| Weaning outcome measures | All patients (n = 263) | Weaning success (n = 126) | Weaning failure (n = 137) | P valuea |
|---|---|---|---|---|
| Weaning success | 126 (47.9) | 126 (100) | – | – |
| Weaning failure | 137 (52.1) | – | 137 (100.0) | – |
| HMV-NIV | 50 (19.0) | – | 50 (36.5) | – |
| HMV-IMV | 74 (28.1) | – | 74 (54.0) | – |
| Death on MV | 13 (4.9) | – | 13 (9.5) | – |
| Weaning duration from first SBT (days) | 22.9 (± 16.1) | 19.0 (± 11.7) | 26.6 (± 18.5) | < 0.001b |
| Duration of mechanical ventilation (days) | 52.2 (± 28.6) | 45.2 (± 22.1) | 58.6 (± 32.1) | < 0.001b |
| Decannulation | 135 (51.3) | 85 (67.5) | 50 (36.5) | < 0.001c |
| SB on discharge from hospital (hours per day)d | 16.1 (± 8.9) | 21.9 (± 6.5) | 10.9 (± 7.5) | < 0.001b |
| LTOT on discharge | 183 (78.9) | 74 (63.8) | 109 (94.0) | < 0.001c |
| Weaning unit-LOS (days) | 48.3 (± 28.5) | 40.8 (± 21.7) | 55.1 (± 32.0) | < 0.001b |
| Hospital-LOS (days) | 52.8 (± 28.6) | 45.6 (± 22.2) | 59.5 (± 32.0) | < 0.001b |
| Hospital mortality | 38 (14.4) | 13 (10.3) | 25 (18.2) | 0.068c |
Continuous variables are presented as mean values (± standard deviation); categorical variables are presented as number (%)
aP value for differences between patients with weaning success and weaning failure
bStudent’s t test
cChi-squared test
dValues for deceased patients were set at 0 h
HMV-NIV home mechanical ventilation-non-invasive mechanical ventilation, HMV-IMV home mechanical ventilation-invasive mechanical ventilation, IMV invasive mechanical ventilation, SB spontaneous breathing, LTOT long-term oxygen therapy, SBT spontaneous breathing trial, LOS length of stay