Table 4.
Variables associated with failure of prolonged weaning and failure of spontaneous breathing trial—results of binary logistic regression model
| Variables | Failure of prolonged weaning | Failure of first SBT | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Gender (male) | 0.532 (0.291–0.973) | 0.040 | 0.401 (0.216–0.745) | 0.004 |
| Obesity (BMI > 30 kg/m2) | 2.595 (1.210–5.562) | 0.014 | – | n.s. |
| COPD | 3.209 (1.563–6.589) | 0.002 | – | n.s. |
| LTC-MP | 3.470 (1.067–11.284) | 0.039 | 3.017 (1.027–8.862) | 0.046 |
| PaCO2 on MV | 1.101 (1.034–1.173) | 0.003 | 1.157 (1.083–1.235) | < 0.001 |
| Failed first SBT | 4.702 (2.250–9.825) | < 0.001 | – | n.a. |
SBT spontaneous breathing trial, OR odds ratio, 95% CI 95% confidence interval, n.s. not significant, BMI body mass index, COPD chronic obstructive pulmonary disease, LTC-MP mechanical power normalized to dynamic lung-thorax compliance, n.s. not significant, MV mechanical ventilation, n.a. not applicable