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. 2020 Feb 21;18:94. doi: 10.1186/s12967-020-02271-6

Table 4.

Correlation between PPARγ, Cox-1 and Cox-2 expression and clinicopathological or aggressiveness related parameters

PPARγ n = 143 to 262 Cox-1 Cox-2
Total Nuclear Cytoplasmic n = 159 to 297 n = 153 to 285
Age 0.004 − 0.050 0.002 0.041 − 0.015
pT 0.118 − 0.037 0.113 − 0.049 − 0.066
pN 0.069 0.023 0.065 − 0.125* − 0.043
Grade 0.007 − 0.205* 0.054 − 0.007 − 0.062
ER − 0.119 0.117 − 0.142* 0.009 0.039
PR − 0.048 0.038 − 0.049 − 0.018 0.012
HER2 0.157** − 0.127* 0.173** 0.137* 0.090
Triple negative 0.076 − 0.062 0.085 − 0.043 − 0.052
Ki-67 0.116 − 0.039 0.119 0.084 0.155*
Focality 0.043 0.074 0.016 − 0.048 − 0.028
CD133 0.221** − 0.007 0.230** 0.132* 0.378**
NCAD 0.412** − 0.196** 0.447** 0.241** 0.461**

Correlations are statistically significant for p < 0.05 (*) or p < 0.01 (**), using Spearman-Rho-Test