Table 5.

Multivariate analysis of significant clinicopathological variables and of cytoplasmic PPARγ regarding OS in the whole cohort and in various subgroups

	Age	pT	ER	HER2	Cytoplasmic PPARγ
Whole cohort
p	0.00001***	0.00000007***	0.008**	0.154	0.129
HR	1.040	3.769	0.508	1.616	1.457
N-cadherin low
p	0.002**	0.00037***	0.015*	0.528	0.044*
HR	1.041	3.370	0.420	1.341	1.996
N-cadherin high
p	0.000733***	0.000032***	0.174	0.035*	0.902
HR	1.045	6.121	0.583	3.437	1.052
Cox-1 negative
p	0.000023***	0.000008***	0.162	0.307	0.014*
HR	1.045	3.835	0.655	1.598	2.047
Cox-1 positive
p	0.017*	0.017*	0.023*	0.253	0.454
HR	1.051	3.574	0.284	1.907	0.670
Cox-2 low
p	0.000002***	0.00008***	0.015*	0.969	0.102
HR	1.058	3.272	0.440	0.983	1.665
Cox-2 high
p	0.112	0.000343**	0.801	0.021*	0.545
HR	1.027	7.681	0.867	5.369	1.427

HR, hazard ratio; p, p-value

In the sub-groups, the same cut-off as in Figs. 2 and 3 have been used, namely 3.5 for N-Cadherin and 7 for Cox-2. Correlations are statistically significant for p < 0.05 (*) or p < 0.01 (**), p < 0.001 (***)