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Summary of common FGFR alterations in brain tumors. Some alterations are strongly associated with low grade neuroepithelial lesions: FGFR1-TKD, FGFR1-TACC1 fusion, FGFR2-CTNNA3 fusion. Others (including FGFR1 hotspot mutations and FGFR3-TACC3 fusions) are described in low-grade as well as high-grade tumors, requiring cautious interpretation when encountered in histologic LGNTs
