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. Author manuscript; available in PMC: 2020 Feb 22.
Published in final edited form as: Mol Pharm. 2019 Jun 27;16(8):3414–3429. doi: 10.1021/acs.molpharmaceut.9b00208

Figure 6.

Figure 6.

Fasudil concentration in the perfusate after the treatments with the plain drug and various liposomal formulations of the drug given via the inhalation-mimicking route (IT instillation) to (A,C) sham and (B,D) PAH lungs. The dose of fasudil was 3 mg/kg (rat body weight) or liposomes containing equivalent amount of fasudil and the dose of CAR was 0.5 mg/kg (data represent mean ± SD, n = 3).