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. 2020 Feb 18;15:1149–1160. doi: 10.2147/IJN.S236922

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© 2020 Xu et al.

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Transportation of RIN loaded nanoparticles across the BBB model in vitro. (A) The schematic diagram of BBB model in vitro. (B) Concentration cellular permeation of RIN when treated as a plain RIN solution, NPS-RIN, and T80-NPS-RIN on mouse brain endothelial (bEnd.3) cell monolayer. (C) The fluctuation of TEER value during the permeation experiment. Results are denoted as mean ± SD (n=3), **P < 0.01, and ***P <0.001.