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. 2020 Feb 18;14:647–659. doi: 10.2147/DDDT.S238955

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© 2020 Bian and Guo.

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In vitro SFN (A) and CCM (B) release of nanoparticles preformed in pH 7.4 and 5.5. The drug release of LAC-SFN/CCM-NPs in pH 5.5 was more efficient than in pH 7.4. At the end of study, over 80% of drugs were released from LAC-SFN/CCM-NPs in pH 5.5, while drugs release in pH 7.4 was less than 60%. Data represent mean ± SD, *means P < 0.05.