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Inflammatory but not patrolling monocytes are implicated in host survival during S. suis systemic infection. Survival of wild-type (black), CCR2−/− (green), and Nr4a1−/− (blue) mice infected with S. suis by intraperitoneal inoculation during the acute systemic infection (until 72 h postinfection). The data represent survival curves (n = 10). * (P < 0.05) indicates a significant difference between survival of wild-type and CCR2−/− mice as determined using the log-rank (Mantel-Cox) test.
