FIG 8.

TcyP is broadly conserved in bacteria. (Top) Domain architecture and cellular localization of the S. aureus TcyP protein (462aa; WP_000991007.1), as characterized by Interproscan, Phobius (see Materials and Methods). The predominant domain, sodium:dicarboxylate symporter superfamily, is indicated in green with the transmembrane (TM) regions shown in blue. The predicted cytoplasmic (c) and noncytoplasmic (nc) regions are labeled for the loop residues. (Bottom) Homologues of TcyP in Firmicutes (blue) and Proteobacteria (orange) using the S. aureus TcyP as the query are shown. Staphylococcus aureus is highlighted in dark blue.