FIG 4.

Representation of CCL2 and CCL7 gene expression ROC curves as predictors of therapeutic outcome. Receiver operating characteristic (ROC) curves represent the area under the curve (AUC) of the false positive rate versus the true positive rate. Data from all samples for each individual gene were used to construct the ROC curves of gene expression data in pretreatment (continuous line) and posttreatment (dotted line) biopsy specimens. P values, AUC, and cutoff values based on Youden’s J statistic are shown in the graph plots.