FIG 6.

Glycocalyx components are increased in plasma for several weeks after admission. (A) PBR persisted to be increased but decreased to levels comparable to those of healthy controls at day 28 postadmission. The bold black line shows the linear regression of the data points. (B) Plasma HA decreased significantly at day 28 postadmission (P = 0.02), while no change in comparison to day 0 was noted at day 14 postadmission (P = 0.4). Also, in UM patients, a time-dependent decrease was seen (P = 0.03, day 0 versus day 28). (C) Plasma syndecan-1 levels were significantly reduced at day 28 in SM patients (P = 0.03). (D) Plasma angiopoietin-1 levels did not change significantly during 28 days postadmission. (E) Plasma levels of angiopoietin-2 decreased but not significantly in comparison with levels at admission. (F) Plasma E-selectin levels were reduced back to normal levels at day 28 postadmission (P = 0.03). All data points represent one individual. Data are summarized as medians, and error bars show 95% confidence intervals. ***, P value of <0.001; **, P value of <0.01 and >0.001; *, P value of <0.05 and >0.01.