Table 1. Antifungal activities of FLC and the fluorescent azoles.
| Compound MIC [μg/mL] | |||||
|---|---|---|---|---|---|
| Yeast strain | FLC | 2 | 3 | 4 | 5 |
| A. C. albicans SC5314 | 1 | 2 | 0.062 | >64 | >64 |
| B. C. albicans 90028 | 0.5 | 2 | 0.007 | >64 | >64 |
| C. C. albicans 24433 | 1 | 2 | 0.125 | >64 | >64 |
| D. C. albicans P-87 | 0.5 | 2 | 0.007 | >64 | >64 |
| E. C. albicans DSY3553 | 0.5 | 4 | 0.125 | >64 | >64 |
| F. C. albicans SN152 | 0.5 | 2 | 0.125 | >64 | >64 |
| G. C. tropicalis 660 | 0.5 | 2 | 0.007 | >64 | >64 |
| H. C. parapsilosis 90018 | 0.5 | 2 | 0.031 | >64 | >64 |
| I. C. parapsilosis 22019 | 1 | 8 | 0.125 | >64 | >64 |
| J. C. guilliermondii B-3163 | 4 | 8 | 0.125 | >64 | >64 |
| K. C. dubliniensis Wu284 | 0.25 | 0.5 | 0.062 | >64 | >64 |
All MICs were determined using the broth double-dilution method starting with 64 μg/mL of each compound.[28] Cells were grown in RPMI 1640 medium at 37° under 5% CO2 for 24 h. Each concentration was tested in triplicate, and results were confirmed by two independent sets of experiments.