Figure 5: Western Blot Analysis of Endoplasmic Reticulum Stress Proteins in Rat Aortic Endothelial Cells Exposed to ZnO Nanoparticles:
RAECs were exposed to pristine, annealed, oxidized or reduced ZnO NPs. (A) Images of key ER stress proteins at 6, 12, and 24 hrs following exposure to ZnO NPs at 20 μg/ml. (B) Densiometric analysis of PERK, IRE and ATF6 protein expression (N=3). *statistically significant compared to control (untreated cells), #statistically significant compared to pristine ZnO NPs (P<0.05).