Table 3.

Cox regression analysis for post-liver transplantation mortality among all patients listed for liver transplant

	Univariable			Multivariable*
	HR	95% CI	P value	HR	95% CI	P value
Age ≥65 (at listing)	1.39	1.33–1.45	<0.001	1.50	1.41 – 1.60	<0.001
HCC	1.13	1.09–1.18	<0.001	1.26	1.18 – 1.33	<0.001
Female gender	0.93	0.90–0.96	<0.001
Liver diagnosis
Alcohol	Ref			Ref
Hepatitis C	1.26	1.21–1.32	<0.001	1.34	1.28 – 1.40	<0.001
NASH	1.06	1.01–1.12	0.02	1.07	1.01 – 1.12	0.02
Autoimmune	0.81	0.77–0.86	<0.001	0.87	0.81 – 0.93	<0.001
Other	1.10	1.02–1.17	0.007	1.11	1.04 – 1.18	0.001
MELD (final) per point	1.01	1.01–1.01	<0.001	1.01	1.01 – 1.02	<0.001
Waiting List Time per 90 days	0.99	0.98 – 0.99	<0.001	0.99	0.98 – 0.997	0.03
KPS per 10 points	1.00	0.00–1.00	<0.001	0.96	0.95 – 0.97	<0.001
Hepatic encephalopathy	1.21	1.16–1.26	<0.001	1.11	1.05 – 1.18	<0.001
Donor risk index per 0.1 points	1.38	1.30–1.47	<0.001	1.03	1.03 – 1.04	<0.001

HR, hazard ratio; CI, confidence interval; HCC, hepatocellular carcinoma; NASH, nonalcoholic steatohepatitis; MELD, model for end stage liver disease; KPS, Karnofsky Performance Status

^*Multivariable model also adjusted for interaction term between age and HCC