Table 1.
Patient demographic, clinical and histopathological characteristics according to sex in the overall cohort (n = 185,967). All differences in relative distributions are highly significant with p < 0.001 according to Pearson’s chi-square test
| Sex | |||||||
|---|---|---|---|---|---|---|---|
| Male | Female | Total | |||||
| N | % | N | % | N | % | ||
| Year of diagnosis | 2000–2004 | 24,947 | 24.9 | 22,831 | 26.6 | 47,778 | 25.7 |
| 2005–2009 | 33,348 | 33.3 | 28,519 | 33.3 | 61,867 | 33.3 | |
| 2010–2016 | 41,987 | 41.9 | 34,335 | 40.1 | 76,322 | 41.0 | |
| Age at diagnosis | 0–49 | 5261 | 5.2 | 4941 | 5.8 | 10,202 | 5.5 |
| 50–59 | 12,795 | 12.8 | 9231 | 10.8 | 22,026 | 11.8 | |
| 60–69 | 29,663 | 29.6 | 18,779 | 21.9 | 48,442 | 26.0 | |
| 70–79 | 36,882 | 36.8 | 29,356 | 34.3 | 66,238 | 35.6 | |
| 80+ | 15,681 | 15.6 | 23,378 | 27.3 | 39,059 | 21.0 | |
| Tumor localization | Right colon | 36,812 | 36.7 | 38,588 | 45.0 | 75,400 | 40.5 |
| Transverse colon | 8419 | 8.4 | 7324 | 8.5 | 15,743 | 8.5 | |
| Left colon | 49,181 | 49.0 | 34,918 | 40.8 | 84,099 | 45.2 | |
| Other locations | 5870 | 5.9 | 4855 | 5.7 | 10,725 | 5.8 | |
| Tumor localization ICDO-3 | Cecum | 13,020 | 13.0 | 15,287 | 17.8 | 28,307 | 15.2 |
| Appendix | 1725 | 1.7 | 2137 | 2.5 | 3862 | 2.1 | |
| Right colon | 16,151 | 16.1 | 16,614 | 19.4 | 32,765 | 17.6 | |
| Right flexure | 5916 | 5.9 | 4550 | 5.3 | 10,466 | 5.6 | |
| Transverse colon | 8419 | 8.4 | 7324 | 8.5 | 15,743 | 8.5 | |
| Left flexure | 3936 | 3.9 | 2766 | 3.2 | 6702 | 3.6 | |
| Left colon | 6065 | 6.0 | 4045 | 4.7 | 10,110 | 5.4 | |
| Colon sigmoideum | 39,180 | 39.1 | 28,107 | 32.8 | 67,287 | 36.2 | |
| Overlapping loc. | 1051 | 1.0 | 789 | 0.9 | 1840 | 1.0 | |
| Other locations | 4819 | 4.8 | 4066 | 4.7 | 8885 | 4.8 | |
| Second tumor (previous, synchronous) | No | 97,846 | 97.6 | 84,151 | 98.2 | 181,997 | 97.9 |
| Yes | 2436 | 2.4 | 1534 | 1.8 | 3970 | 2.1 | |
| Histological type | Adenocarcinoma | 95,727 | 95.5 | 81,201 | 94.8 | 176,928 | 95.1 |
| Neuroendocr. Ca | 1636 | 1.6 | 1824 | 2.1 | 3460 | 1.9 | |
| Other carcinoma | 2728 | 2.7 | 2470 | 2.9 | 5198 | 2.8 | |
| Other tumor lesions | 191 | 0.2 | 190 | 0.2 | 381 | 0.2 | |
| Grading | G1 | 6488 | 6.5 | 5184 | 6.1 | 11,672 | 6.3 |
| G2 | 65,544 | 65.4 | 52,578 | 61.4 | 118,122 | 63.5 | |
| G3/4 | 21,029 | 21.0 | 21,666 | 25.3 | 42,695 | 23.0 | |
| Unspecified | 7221 | 7.2 | 6257 | 7.3 | 13,478 | 7.2 | |
| UICC stage | I | 19,932 | 19.9 | 15,353 | 17.9 | 35,285 | 19.0 |
| II | 25,381 | 25.3 | 22,234 | 25.9 | 47,615 | 25.6 | |
| III | 21,052 | 21.0 | 19,445 | 22.7 | 40,497 | 21.8 | |
| IV | 22,938 | 22.9 | 18,956 | 22.1 | 41,894 | 22.5 | |
| X | 10,979 | 10.9 | 9697 | 11.3 | 20,676 | 11.1 | |
| Total | 100,282 | 100.0 | 85,685 | 100.0 | 185,967 | 100.0 | |