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In vivo efficacy of MEFTN in tumor xenograft models.
| Groups | Ovarian (PA1) | Lung (A549) |
|---|---|---|
| Tumor size (mm3) after the treatment period | ||
| Untreated | 354 ± 7.1 | 426 ± 60 |
| MEFTN | 89 ± 15 | 170 ± 43 |
Xenograft models were generated in nude mice. MEFTN (300 mg/kg BW p.o. BID) was fed orally in treated groups, and vehicle was fed to the untreated group for 31 days in ovarian and 14 days in lung cancer. Mean ± SD was indicated in the result.
