Table 1.
Description of 40 proteins cocrystallized with the flavonoid scaffold.
| PDB ID | Name | Uniprot ID | Protein length | Organism |
|---|---|---|---|---|
| 6MS8 | Chalcone-flavonone isomerase family protein | B7FJK3 | 224 | Medicago truncatula |
| 6G8H | TetR/AcrR family transcriptional regulator | A0A2A6N3G4 | 214 | Bradyrhizobium diazoefficiens |
| 6AWT, 6AWV, | ||||
| 6AX0, 4MA6 | Ara h 8 allergen | Q6VT83 | 157 | Arachis hypogaea |
| 6DHL | Glutamate dehydrogenase 1 | P00366 | 496 | Bos taurus |
| 6F6A | Glutathione transferase | A0A384E145 | 246 | Trametes versicolor |
| 5WKR, 5WKS | Engineered chalcone isomerase | N/A | 223 | N/A |
| 5J3J | Dipeptidyl peptidase-4 | P27487 | 734 | Homo sapiens |
| 5F8P | Alpha-ketoglutarate-dependent dioxygenase FTO | Q9C0B1 | 476 | Homo sapiens |
| 5JDC | Pteridine reductase | O76290 | 288 | Trypanosoma brucei brucei |
| 4D06 | Chalcone isomerase | V9P0A9 | 283 | Eubacterium ramulus |
| 4KZQ | Tankyrase-2 | Q9H2K2 | 191 | Homo sapiens |
| 4C94 | Pathogenesis-related 10 (Pr-10) Fra a 3 | D0E0C7 | 161 | Fragaria ananassa |
| 4C9I | Pathogenesis-related 10 (Pr-10) Fra a 1E | Q256S2 | 162 | Fragaria ananassa |
| 4EH3 | Mitogen-activated protein kinase 14 | Q16539 | 360 | Homo sapiens |
| 4DEU, 3NG5 | Transthyretin | P02766 | 147 | Homo sapiens |
| 4AWM | Polymerase acidic protein | C3W5S0 | 192 | Influenza A virus |
| 4A87 | Major pollen allergen bet V 1-A | P15494 | 159 | Betula pendula |
| 3TVQ | Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN | P16559 | 169 | Streptomyces glaucescens |
| 3OOB | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Q13526 | 163 | Homo sapiens |
| 3I52 | Putative leucoanthocyanidin reductase 1 | Q4W2K4 | 346 | Vitis vinifera |
| 3D04 | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase | Q5G940 | 159 | Helicobacter pylori |
| 2KDH | Troponin C | P63316 | 72 | Homo sapiens |
| 2NNL | Dihydroflavonol 4-reductase | P51110 | 337 | Vitis vinifera |
| 2UXU | HTH-type transcriptional regulator TtgR | Q9AIU0 | 210 | Pseudomonas putida |
| 2C29 | Dihydroflavonol 4-reductase | P93799 | 337 | Vitis vinifera |
| 2BRT, 1GP5 | Leucoanthocyanidin dioxygenase | Q96323 | 356 | Arabidopsis thaliana |
| 1JNQ | Lipoxygenase-3 | P09186 | 857 | Glycine max |
| 1JX0, 1JX1 | ||||
| 1FM7, 1FM8 | Chalcone-flavonone isomerase 1 | P28012 | 222 | Medicago sativa |
| 1JEP, 1EYQ | ||||
| 1CGK | Chalcone synthase | P30074 | 389 | Medicago sativa |