Table 3.
Univariate and multivariate analysis for overall survival after recurrence
| Factors | Number | Univariate | Multivariate | ||
|---|---|---|---|---|---|
| HR(95%CI) | P | HR(95%CI) | P | ||
| Pathological N stage | <0.001 | <0.001 | |||
| pN0 | 106 | 1 | 1 | ||
| pN+ | 87 | 1.984(1.438–2.737) | 0.507(0.360–0.714) | ||
| Pathological TNM stage | <0.001 | – | – | ||
| I/II | 116 | 1 | |||
| III | 77 | 2.353(1.697–3.263) | |||
| Salvage treatment | <0.001 | <0.001 | |||
| SCRT | 48 | 1 | 1 | ||
| SRT | 109 | 1.510(1.002–2.276) | 0.049 | 1.419(0.940–2.142) | 0.096 |
| No RT | 36 | 4.175(2.529–6.891) | <0.001 | 3.246(1.931–5.458) | <0.001 |
| Site of recurrence | 0.002 | – | – | ||
| Above the diaphragm | 139 | 1 | |||
| Along with upper abdominal LN recurrence | 24 | 1.967(1.234–3.136) | 0.004 | ||
| Along with hematogenous metastases | 30 | 1.816(1.177–2.804) | 0.007 | ||
| Number of LN recurrence regions | 0.042 | – | – | ||
| Single region | 83 | 1 | |||
| Multiple regions | 110 | 1.408(1.012–1.958) | |||