Table 1.
Characteristics of the subjects stratified by gender and serum urate quartiles
| Men (N = 508) | Women (N = 532) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total, (N = 508) | 1st quartile 31–307 μmol/L (N = 124) | 2nd quartile 308–346 μmol/L (N = 132) | 3rd quartile 347–391 μmol/L (N = 127) | 4th quartile 392–584 μmol/L (N = 125) | Total (N = 532) | 1st quartile 143–229 μmol/L (N = 132) | 2nd quartile 230–262 μmol/L (N = 131) | 3rd quartile 263–304 μmol/L (N = 135) | 4th quartile 305–702 μmol/L (N = 134) | |
| Age in years, mean (SD) | 57.7 (4.4) | 57.8 (4.5) | 57.8 (4.4) | 56.9 (4.6) | 58.2 (4.1) | 57.5 (4.3) | 56.8 (4.0) | 57.6 (4.4) | 57.5 (4.2) | 58.3 (4.6) |
| BMI, mean (SD) | 27.7 (4.1) | 26.1 (3.2) | 27.3 (3.6) | 28.3 (4.0) | 29.2 (4.7) | 26.8 (4.9) | 24.5 (3.6) | 25.2 (3.4) | 26.9 (4.5) | 30.4 (5.7) |
| Smoking, N (%) | ||||||||||
| Never | 215 (42) | 49 (40) | 66 (50) | 53 (42) | 47 (38) | 237 (45) | 51 (39) | 60 (46) | 66 (49) | 60 (45) |
| Occasional | 12 (2) | 3 (2) | 2 (2) | 5 (4) | 2 (2) | 23 (4) | 10 (8) | 5 (4) | 4 (3) | 4 (3) |
| Previous | 206 (41) | 48 (39) | 49 (37) | 51 (41) | 58 (46) | 191 (36) | 47 (36) | 46 (35) | 51 (38) | 47 (35) |
| Active | 74 (15) | 24 (19) | 16 (12) | 16 (13) | 18 (14) | 79 (15) | 23 (18) | 20 (15) | 14 (10) | 22 (17) |
| Physical activity, N (%) | ||||||||||
| Less than 2 h per week | 89 (18) | 22 (18) | 21 (16) | 24 (20) | 22 (18) | 75 (14) | 14 (11) | 9 (7) | 20 (15) | 32 (24) |
| Moderate, for at least 2 h per week to induce a sweat | 205 (41) | 50 (41) | 48 (36) | 51 (42) | 56 (45) | 242 (46) | 65 (50) | 57 (44) | 58 (43) | 62 (47) |
| Moderate and regularly, at least one or two times per week and for at least 30 min | 140 (28) | 29 (24) | 45 (34) | 32 (26) | 34 (27) | 120 (23) | 29 (22) | 34 (26) | 29 (22) | 28 (21) |
| Regularly, at least three times per week and for at least 30 min | 68 (14) | 21 (17) | 18 (14) | 16 (13) | 13 (10) | 91 (17) | 23 (18) | 31 (24) | 27 (20) | 10 (8) |
| eGFR, N (%) | ||||||||||
| eGFR, > 90 mL/min | 180 (35) | 64 (52) | 46 (34) | 40 (32) | 30 (24) | 467 (88) | 125 (95) | 118 (90) | 116 (86) | 108 (81) |
| eGFR, 60–90 mL/min | 316 (62) | 60 (48) | 85 (63) | 82 (66) | 89 (71) | 60 (11) | 5 (4) | 13 (10) | 17 (13) | 25 (19) |
| eGFR, < 60 mL/min | 12 (2) | 0 (0) | 3 (2) | 3 (2) | 6 (5) | 5 (1) | 2 (2) | 0 (0) | 2 (2) | 1 (1) |
| SU, μmol/L, mean (SD) | 353 (67) | 273 (34) | 327 (12) | 370 (12) | 441 (40) | 270 (63) | 200 (22) | 245 (10) | 281 (12) | 353 (52) |
| hs-CRP, mean (SD) | 2.2 (3.4) | 1.7 (2.8) | 1.6 (1.6) | 2.5 (2.9) | 3.1 (5.2) | 2.4 (3.8) | 1.4 (1.4) | 2.2 (5.7) | 2.1 (2.7) | 3.9 (3.7) |
| Hypertension, N (%) | 160 (32) | 26 (21) | 38 (29) | 47 (40) | 49 (40) | 178 (34) | 30 (23) | 35 (28) | 47 (36) | 66 (50) |
| Diabetes, N (%) | 39 (8) | 10 (8) | 11 (8) | 10 (8) | 8 (7) | 21(4) | 6 (5) | 3 (2) | 3 (2) | 9 (7) |
| Dyslipidemia, N (%) | 144 (30) | 30 (25) | 38 (30) | 35 (30) | 41 (35) | 121 (24) | 28 (22) | 29 (23) | 22 (17) | 42 (34) |
| CAC+, N (%) | 293 (58) | 59 (48) | 80 (60) | 73 (58) | 81 (65) | 137 (26) | 31 (24) | 31 (24) | 33 (25) | 42 (31) |
| CIMT+, N (%)* | 106 (24) | 24 (22) | 34 (30) | 20 (19) | 28 (27) | 117 (25) | 24 (21) | 29 (24) | 31 (26) | 33 (29) |
| Plaque+, N (%)* | 308 (61) | 68 (55) | 88 (66) | 72 (58) | 80 (64) | 268 (51) | 68 (52) | 60 (47) | 71 (53) | 69 (52) |
CAC+: total CAC score > 0
CIMT+: CIMT > 75th percentile
Plaque+: plaque score > 0
*Because of missing values, the total number of subjects in each urate quartile is:
For CIMT and men: 1st quartile N = 111, 2nd quartile N = 115, 3rd quartile N = 106, and 4th quartile N = 104
For CIMT and women: 1st quartile N = 117, 2nd quartile N = 123, 3rd quartile N = 120, and 4th quartile N = 115
For plaque score and men: 1st quartile N = 124, 2nd quartile N = 133, 3rd quartile N = 125, and 4th quartile N = 125
For plaque score and women: 1st quartile N = 131, 2nd quartile N = 128, 3rd quartile N = 134, and 4th quartile N = 133