Fig. 2.

Summary of FilmArray ME positive result (dark gray). Light gray bars indicate disconcordant results, e.g. positive FilmArray ME results that could neither be confirmed by standard cultural methods nor by molecular testing. For S. pneumoniae, one sample could not be confirmed by specific PCR nor by cultural methods, whereas n = 16 samples were confirmed by specific PCR and n = 12 of FilmArray ME positive samples were confirmed by both methods. For S. agalactiae, one of the FilmArray ME positive samples could neither be confirmed by cultural methods nor by specific PCR. For E.coli K1 detected in FilmArray ME also no confirmation was obtained by any method. One sample was designated HSV-1 positive by FilmArray ME, but no such pathogen could be detected by two different specific quantitative real-time PCRs. HHV-6 was detected in four samples by Film Array ME, two of those yielded a double hit (positive for HHV-6 and VZV or H. influenzae and HHV-6, respectively). Conventional assays confirmed presence of VZV and H. influenzae, whereas HHV-6 was not found by specific PCR