Table 2. Univariate analysis results of allele and genotype frequency.
| Allele frequency n(%) | Genotype frequency n(%) | HWE P | |||||
|---|---|---|---|---|---|---|---|
| rs1801133 | C | T | CC | CT | TT | ||
| Case group* | 125(38.34) | 201(61.66) | 28(17.18) | 69(42.33) | 66(40.49) | >0.05 | |
| Control group | 325(49.85) | 327(50.15) | 106(32.52) | 113(34.66) | 107(32.82) | >0.05 | |
| rs1801131 | A | C | AA | AC | CC | ||
| Case group* | 282(86.50) | 44(13.50) | 126(77.30) | 30(18.40) | 7(4.30) | >0.05 | |
| Control group | 516(79.14) | 136(20.86) | 219(67.18) | 78(23.93) | 29(8.90) | >0.05 | |
| rs2274976 | A | G | AA | AG | GG | ||
| Case group | 28(8.59) | 298(91.41) | 2(1.22) | 24(14.72) | 137(84.05) | >0.05 | |
| Control group | 61(9.36) | 591(90.64) | 6(1.84) | 49(15.03) | 271(83.13) | >0.05 | |
| rs4846048 | A | G | AA | AG | GG | ||
| Case group | 288(88.34) | 38(11.66) | 125(76.69) | 38(23.31) | 0(0) | >0.05 | |
| Control group | 581(89.11) | 71(10.89) | 255(78.22) | 71(21.78) | 0(0) | >0.05 | |
| rs4846049 | G | T | GG | GT | TT | ||
| Case group | 263(80.67) | 63(19.33) | 106(65.03) | 51(31.29) | 6(3.68) | >0.05 | |
| Control group | 525(80.52) | 127(19.48) | 213(65.34) | 99(30.37) | 14(4.29) | >0.05 | |
| rs13306561 | C | T | CC | CT | TT | ||
| Case group | 29(8.90) | 297(91.10) | 3(1.84) | 23(14.11) | 137(84.05) | >0.05 | |
| Control group | 53(8.13) | 599(91.87) | 4(1.23) | 45(13.80) | 277(84.97) | >0.05 | |
| rs3737964 | A | G | AA | AG | GG | ||
| Case group | 37(11.35) | 289(88.65) | 0(0) | 37(22.70) | 126(77.30) | >0.05 | |
| Control group | 73(11.20) | 579(88.80) | 0(0) | 73(22.39) | 253(77.61) | >0.05 | |
Notes.
*
P < 0.05, vs allele frequency and genotype frequency of the control group.
HWE, Hardy–Weinberg equilibrium