eTable. Concomitant secondary diagnoses (ICD-10-GM codes) for outpatient or inpatient treatment in the investigated period.
| Secondary diagnoses*1 | ALF patients with diagnosis | ALF patients with diagnosis and LT | ||
| (n) | (% of all ALF patients)*2 | (n) | (% of ALF patients with diagnosis) | |
| Liver disease*3 | ||||
| B15 acute viral hepatitis A | 118 | 2.6 | 3 | 2.8 |
| B16 acute viral hepatitis B | 244 | 5.3 | 4 | 1.6 |
| B17.0 acute viral hepatitis D | 7 | 0.2 | 0 | – |
| B17.1 acute viral hepatitis C | 64 | 1.4 | 0 | – |
| B17.2 acute viral hepatitis E | 162 | 3.5 | 11 | 6.5 |
| B25.1 cytomegaloviral hepatitis | 23 | 0.5 | 4 | 17.3 |
| B27 infectious mononucleosis | 96 | 2.1 | 26 | 26.5 |
| E83.0 disorders of copper metabolism (Wilson’s disease) | 26 | 0.6 | 11 | 44.4 |
| I82.0 Budd-Chiari syndrome | 48 | 1.0 | 11 | 22.5 |
| K70 alcoholic liver disease (without K70.3. K70.4) | 196 | 4.2 | 0 | – |
| K71 toxic liver disease (without K71.7) | 946 | 20.5 | 56 | 6.0 |
| K75.4 autoimmune hepatitis | 352 | 7.6 | 27 | 7.6 |
| K76.0 fatty change of liver | 843 | 18.2 | 23 | 2.7 |
| T36-T50 poisoning by drugs, medications, and biologically active substances (without T39.1) | 277 | 6.0 | 11 | 4.0 |
| T39.1 poisoning by 4-aminophenol derivatives*4 | 176 | 3.8 | 4 | 2.0 |
| T62.0 toxic effect of ingested mushrooms | 96 | 2.1 | 7 | 7.5 |
| General condition | ||||
| C00-C99 malignant neoplasms (without C22, C23, C24, C78.7) | 1143 | 24.7 | 35 | 3.0 |
| E10-E14 diabetes mellitus | 1524 | 33.0 | 42 | 2.8 |
| F10 mental behavioral disorders due to use of alcohol | 668 | 14.5 | 15 | 2.3 |
| I25 chronic ischemic heart disease | 1212 | 26.2 | 7 | 0.6 |
| J44 chronic obstructive pulmonary disease | 970 | 21.0 | 16 | 1.6 |
*1 Multiple assessments possible.
*2 Total of 4621 patients.
*3 2574 patients without diagnoses B15, B16, B17.0, B17.1, B17.2, B25.1, B27, E83.0, I82.0, K71, K75.4, T36-T50 including T39.1, T62.0; diagnoses K70 and K76.0 are not considered causes of ALF in a narrower sense.
*4 Including acetaminophen, phenacetin is no longer approved in Germany
ALF, Acute liver failure; ICD-10-GM, International Statistical Classification of Diseases and Related Health Problems, 10th revision, German Modification; LT, liver transplantation