Fig. 1.

Two practical DEL typing strategies for serologically D-negative Asian donors. Using our data, aninitial screening method using RhCE phenotyping was predicted to exclude only donors with RHD null alleles. Serologically D-negative donors with C+ phenotypes were tested by RHD genotyping or the adsorption-elution test. Using RHD genotyping, the D-negative donor pool was predicted to contain only donors with RHD null alleles. Using the adsorption-elution test, 0.7% (5/674) of serologically D-negative donors were expected to have the potential to cause anti-D alloimmunization.