Figure 8.

Summary of experimental outcomes in adult mice. Sensory neurons from DRG at different spinal levels contain either entirely somatic sensory neurons (S) or a mixture of somatic and visceral (V) neurons. Genes differentially expressed between DRG at these spinal levels indicate features of pelvic visceral sensory neurons and are represented here by volcano plots (all genes) and heat maps (GPCRs). Very few genes are differentially expressed between males and females. Isolation of Trpv1-expressing nociceptors provides a more sensitive assay for revealing genes differentially expressed between spinal levels (all genes and GPCRs shown as per upper panel) and sex differences.