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Frequency of RAS and Ras-pathway mutations in pediatric hematologic malignancies. (A) RAS and Ras-pathway mutations in all patients; (B) RAS and Ras-pathway mutations in ALL; (C) percentage of RAS and Ras pathway aberrations in AML; (D) frequency of genetic mutations identified to predict hyperactive Ras signaling in sequenced patients. ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia.
