Table 2. Clinical characteristics of five patients with leukocyte adhesion deficiency type I (LAD-I) included in the current study.

Patient	Gender	Age at diagnosis (m)	Granulocytosis (×109/L)	CD18+ leukocytes	Gene defect	Zygosity	Mutations	Infections
1	Male	4	20–117	2.4%	ITGB2	Homozygous	exon7 c.817G>A, p.G273R	Omphalitis, pneumonia, sepsis, intestinal infection
2	Female	23	18–76	3.6%	ITGB2	Compound heterozygous	exon13 c.1794dupC p.N599Qfs*93; exon7 c.850G>A, p.G284S	Omphalitis, pneumonia, skin and soft tissue infection
3	Male	8	14–66	3.4%	ITGB2	Compound heterozygous	exon13 c.1788C>A, p.C596X; exon7 c.817G>A, p.G273R	Omphalitis, pneumonia, skin and soft tissue infection, urinary tract infection
4	Female	13	19–69	2.5%	ITGB2	Homozygous	exon7 c.841_849del9	Pneumonia, sepsis, intracranial infection
5	Female	120	11–52	0.8%	ITGB2	Compound heterozygous	exon7 c.769C>T, p.Arg257Trp; exon6 c.533C>T, p.Pro178Leu	Pneumonia, intestinal infection, skin and soft tissue infection, dental ulcer and gingivitis