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Patient 1 imaging and pathological results. T1-weighted magnetic resonance imaging of Patient 1 shows marked left anterior temporal lobe (ATL) atrophy (A) and left-sided dorsal parietal atrophy (B). Autopsy of Patient 1 shows severe left temporopolar atrophy (C). Hematoxylin and eosin stain of left ATL reveals severe microvacuolation but no infarct (D).
