Figure 3.
T39 ASO induces a Type I IFN response in both WT and T39−/− mice. T39−/− mice and WT littermates were treated with either the control ASO or T39 ASO and placed on the HFSC diet for a total of 10 weeks. A) Weight gain was monitored weekly and B-D) RNAseq was performed on gWAT samples. B) Heatmap of all significant gene changes C) A plot of the GO.