Skip to main content
. 2019 Oct 18;118(4):790–797. doi: 10.1016/j.bpj.2019.10.010

Figure 6.

Figure 6

The PAS-cap binding site. (a) A zoom of the PAS-cap binding site in hERG; Cα of V3 is shown as a sphere, and R4 and R5 are shown as white sticks. Residues within interacting distance (4 Å) of V3 and arginines are shown as yellow sticks. (b) A zoom of PAS-cap binding site in rEAG (light green) and hERG (pink) channels superposed through selectivity filter. Spheres indicate Cα of first residue in PAS-cap: V3 (hERG) and L10 (rEAG). Arrow indicates movement of C-linker helix as the gate closes in rEAG, disassembling PAS-cap binding site.