Figure 4.

(a) The relative distribution of SPT trajectories of serotonin_1A receptors in HEK-293 cells among the four diffusion modes observed in the absence (blue bars, n = 133) and presence (red hatched bars, n = 117) of 5 μM CD. (b) Average short-term diffusion coefficient (D_1–2 (μm² s⁻¹)) of the serotonin_1A receptor measured by SPT on HEK-293 cells is shown for each diffusion mode in the absence (blue bars) and presence (red hatched bars) of 5 μM CD. Data represent means ± SE of at least four independent experiments with at least eight cells for each experiment (^∗, ^∗∗ correspond to significant (p < 0.05), (p < 0.01) differences in short-term diffusion coefficient (D_1–2 (μm² s⁻¹)) for cells treated with CD relative to control). The number of trajectories analyzed in each condition is given in Table 1. See text for more details. To see this figure in color, go online.