Table 1.
Summary of Single-Channel SKM Results
| Construct | Po | Mean Open Time (ms) | MCT (ms) | Po,burst | MCTburst (ms) | Unitary Amplitude (pA) | Total nevents | Total Time (min) |
|---|---|---|---|---|---|---|---|---|
| GluN1–2a/GluN2A (pre) | 0.32 ± 0.07 | 3.6 ± 0.1 | 12.4 ± 6.5 | 0.57 ± 0.01 | 2.7 ± 0.1 | 9.7 ± 0.2 | 32,7900 | 59 |
| GluN1–2a/GluN2A (post) | 0.06 ± 0.01a | 3.5 ± 0.4 | 88 ± 27a | 0.44 ± 0.04a | 4.5 ± 0.7 | 9.5 ± 0.2 | 89,437 | 91 |
| GluN1–2a/GluN2B (pre) | 0.13 ± 0.01 | 3.3 ± 0.3 | 22.1 ± 2.9 | 0.34 ± 0.02 | 6.2 ± 0.4 | 10.2 ± 0.5 | 108,821 | 43 |
| GluN1–2a/GluN2B (post) | 0.07 ± 0.02a | 5.1 ± 0.5a | 87.3 ± 28.3 | 0.39 ± 0.04 | 8.2 ± 0.5a | 9.8 ± 0.4 | 69,871 | 83 |
All values reported as mean ± SE unless otherwise indicated.
a
p < 0.05 two-tailed t-test compared to preionomycin control.