Table 2.
Summary of Single-Channel Dwell-Time Fit Results
| Construct | Closed |
Open |
||||
|---|---|---|---|---|---|---|
| τ1 (A1) | τ2 (A2) | τ3 (A3) | τ4 (A4) | τ5 (A5) | τo, Ao | |
| GluN1–2a/GluN2A (pre) | 0.23 ± 0.01 | 2.18 ± 0.07 | 6.9 ± 0.4 | 27 ± 5 | 3915 ± 2492 | 4.2 ± 0.1 |
| (0.31 ± 0.01) | (0.33 ± 0.01) | (0.34 ± 0.02) | (0.02 ± 0.01) | (0.001 ± 0.001) | (1.00) | |
| GluN1–2a/GluN2A (post) | 0.29 ± 0.01a | 3.55 ± 0.63 | 15.4 ± 2.9a | 1211 ± 895 | 5426 ± 1311 | 3.8 ± 0.4 |
| (0.27 ± 0.01) | (0.41 ± 0.06) | (0.27 ± 0.04) | (0.04 ± 0.02) | (0.01 ± 0.01a) | (1.00) | |
| GluN1–2a/GluN2B (pre) | 0.28 ± 0.01 | 2.61 ± 0.12 | 12.9 ± 1.1 | 54 ± 5 | 1385 ± 88 | 3.5 ± 0.3 |
| (0.22 ± 0.01) | (0.19 ± 0.01) | (0.52 ± 0.01) | (0.05 ± 0.01) | (0.01 ± 0.01) | (1.00) | |
| GluN1–2a/GluN2B (post) | 0.29 ± 0.01 | 3.04 ± 0.11a | 19.9 ± 0.8a | 66 ± 5 | 4473 ± 2341 | 5.5 ± 0.5a |
| (0.24 ± 0.01) | (0.25 ± 0.01a) | (0.44 ± 0.02a) | (0.04 ± 0.01) | (0.02 ± 0.01a) | (1.00) | |
All time constants are reported as mean ± SE in units of ms.
a
p < 0.05 two-tailed t-test compared to preionomycin control.