Table 1.
WT |
OIM+/− |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Control | RAL | ZOL | RAL + ZOL | p-Value | Control | RAL | ZOL | RAL + ZOL | p-Value | |
Total CSA (mm2) | 2.031 ± 0.174 | 2.068 ± 0.193 | 2.011 ± 0.216 | 2.053 ± 0.19 | 0.877 | 1.897 ± 0.267 | 1.837 ± 0.167 | 1.965 ± 0.31 | 1.834 ± 0.194 | 0.712 |
Marrow Area (mm2) | 1.051 ± 0.1 | 1.047 ± 0.116 | 1.027 ± 0.104 | 1.028 ± 0.102 | 0.891 | 0.974 ± 0.128 | 0.902 ± 0.096 | 0.979 ± 0.157 | 0.906 ± 0.116 | 0.273 |
Cortical Area (mm2) | 0.98 ± 0.113 | 1.02 ± 0.084 | 0.984 ± 0.129 | 1.024 ± 0.107 | 0.583 | 0.923 ± 0.179 | 0.935 ± 0.092 | 0.987 ± 0.176 | 0.929 ± 0.091 | 0.951 |
Cortical Thickness (mm) | 0.227 ± 0.021 | 0.235 ± 0.01 | 0.23 ± 0.021 | 0.238 ± 0.017 | 0.371 | 0.225 ± 0.04 | 0.231 ± 0.017 | 0.238 ± 0.036 | 0.229 ± 0.013 | 0.939 |
Periosteal perimeter (mm) | 5.868 ± 0.231 | 5.921 ± 0.239 | 5.852 ± 0.271 | 5.898 ± 0.24 | 0.881 | 5.684 ± 0.357 | 5.63 ± 0.25 | 5.789 ± 0.395 | 5.611 ± 0.254 | 0.758 |
Endocortical perimeter (mm) | 4.581 ± 0.224 | 4.533 ± 0.242 | 4.53 ± 0.282 | 4.5 ± 0.218 | 0.839 | 4.414 ± 0.301 | 4.286 ± 0.265 | 4.513 ± 0.543 | 4.247 ± 0.256 | 0.327 |
Imax (mm4) | 0.346 ± 0.064 | 0.366 ± 0.061 | 0.347 ± 0.074 | 0.366 ± 0.067 | 0.739 | 0.3 ± 0.084 | 0.301 ± 0.058 | 0.329 ± 0.081 | 0.292 ± 0.058 | 0.839 |
Imin (mm4) | 0.168 ± 0.031 | 0.177 ± 0.035 | 0.165 ± 0.041 | 0.174 ± 0.035 | 0.826 | 0.151 ± 0.045 | 0.139 ± 0.025 | 0.166 ± 0.073 | 0.142 ± 0.032 | 0.738 |
TMD (g/cm3) | 1.272 ± 0.021 | 1.267 ± 0.048 | 1.277 ± 0.024 | 1.28 ± 0.021 | 0.698 | 1.309 ± 0.032 | 1.314 ± 0.031 | 1.307 ± 0.035 | 1.314 ± 0.037 | 0.954 |
Values are presented as mean ± standard deviation. CSA - cross sectional area; Imax - maximum moment of inertia; Imin - minimum moment of inertia; TMD - tissue mineral density. There was not a main ANOVA effect in any of the properties.