AMPs |
antimicrobial peptides |
Ac |
acetyl group |
Boc |
tert-butyloxycarbonyl |
C4
|
butanoic acid residue |
C6
|
hexanoic acid residue |
C8
|
octanoic acid residue |
C10
|
decanoic acid residue |
C12
|
dodecanoic acid residue |
C14
|
tetradecanoic acid residue |
CAC |
critical aggregation concentration |
CD |
circular dichroism |
CFU |
colony forming unit |
DCM |
dichloromethane |
DHPC |
l,2-diheptanoyl-sn-glycero-3-phosphocholine |
DIC |
N,N′-diisopropylcarbodiimide |
DMF |
N,N-dimethylformamide |
DMSO |
dimethyl sulfoxide |
DOSY |
Diffusion-Ordered Spectroscopy |
DPC |
dodecylphosphocholine |
EDTA |
ethylenediaminetetraacetic acid |
ESI MS |
electrospray ionization mass spectrometry |
ESKAPE bacteria |
Enterococcus faecium, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella aerogenes, Staphylococcus aureus
|
Fmoc |
9-fluorenylmethoxycarbonyl |
GM |
geometric mean |
HAIs |
hospital-acquired infections |
hRBCs |
human red blood cells |
IC50
|
half maximal inhibitory concentration |
MBEC |
minimal biofilm eradication concentration |
MDR |
multidrug-resistant |
MHC |
minimal hemolytic concentration |
MIC |
minimal inhibitory concentration |
MRSA |
methicillin-resistant S. aureus
|
MTT |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide |
Pbf |
2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl residue |
PBS |
phosphate buffered saline |
POPC |
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine |
POPG |
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol |
RP-HPLC |
reversed-phase high-performance liquid chromatography |
SDS |
sodium dodecyl sulfate |
SI |
selectivity index |
SPPS |
solid-phase peptide synthesis |
TFA |
trifluoroacetic acid |
TIS |
triisopropylsilane |
WHO |
World Health Organization |