AR	Androgen receptor
CRPC	Castration-resistant prostate cancer
CRPC-NE	Castration-resistant prostate cancer neuroendocrine
CF	Cystic fibrosis
ESC	Embryonic stem cells
iPSCs	Induced-pluripotent stem cells
iDOs	iPSC-derived organoids
PAM	Protospacer-adjacent motif
PDOs	Patient-derived organoids
PDXs	Patient-derived xenografts
PSA	Prostate-specific antigen
sgRNA	Single-guide RNA sequence
UGM	Urogenital mesenchyme