Table 1.

Toxicological studies of methomyl in humans and animals.

S.No.	Study Sample/Sample Sources	Concentration/Volume of Methomyl	Specific Statement	References
1	Tilapia	3.2-10 mg L−1	Genotoxicity caused by methomyl	[35]
2	Tilapia	0.2-200 µg L−1	Injury to and apoptosis of testicular tissue	[36]
3	Tilapia	0.2-200 μg L−1	Inhibition of the antioxidant system	[37]
4	Tilapia	0.2-200 μg L−1	Disruption of the endocrine system and genetic variation	[38]
5	Frogs	8.69 mg L−1	Reduced growth rates and tissue damage	[16]
6	Frogs	10 mg L−1	Methomyl induces teratogenicity and neurotoxicity	[17]
7	Frogs	15.43 mg L−1	Death of or deformations in tadpoles	[39]
8	Rats	17 mg kg−1	Inhibition of the reproductive system	[40]
9	Rats	0.25-2.5 mg kg−1	Inhibited activity of brain ChE and RBC ChE	[41]
10	Rats	0.5-20 mg kg−1	Inhibition of the reproductive system	[42]
11	Rats	10 mg kg−1	Inhibition of liver function and enzyme activity	[43]
12	Human	unknown	17 people poisoned (2012–2016, France)	[18]
13	Human	570 μg L−1	Death by inhalation of too much methomyl	[19]
14	Human	Unknown	The person died after swallowing methomyl	[20]
15	Human	300 cm3	Reversible cortical blindness and continuous peeling	[21]
16	Cells	6-30 mmol L−1	DNA damage and apoptosis induced by methomyl	[44]
17	Zooplankton and fish	8 μg L−1	Reduction in the efficiency of the food chain in a Cr/Dg system	[34]