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(A–D) Induction of apoptosis by different kinds of Dox species in Hela cells. Hela cells were treated with free-Dox (100 nM), (FK)2-Dox (100 nM of Dox) or FKK-Dox and analyzed 24 h after the treatment. Raw data for a representative experiment was shown. (E) The apoptotic cell ratio in different groups of cells after treated with free-Dox (100 nM), (FK)2-Dox (100 nM of Dox) or FKK-Dox. Three independent replications were performed. Error bars are SD.
