Figure 1.

Evaluation of the level of platelet activation status in septic patients (n = 21) via surface P-selectin positivity (A) and soluble P-selectin levels (B) measured in some selected plasma samples (n = 10/group) in comparison to controls. Mean platelet volume values were also analyzed to estimate the pool of larger and younger platelets (C). All these parameters were significantly higher than controls, suggesting an enhanced level of platelet activation status after the development of sepsis. Dots represent single results, and median values are depicted. Mann-Whitney U test was performed for comparison.