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. 2020 Jan 30;21(3):917. doi: 10.3390/ijms21030917

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Role of PEG35 on the modulation of pro-inflammatory cytokines and chemokines expression in sodium taurocholate acute necrotizing pancreatitis and associated acute lung injury. (A) IL6 expression levels in plasma. (B) Pancreatic tissue gene expression of IL6, IL1β, CXCL2 and TNFα by real-time qRT-PCR. (C) Lung tissue gene expression of IL6, IL1β, CXCL2 and TNFα by real-time qRT-PCR. In all cases, mRNA induction levels were normalized to GAPDH mRNA expression. Bars represent mean values of each group ± SEM. * p < 0.05 versus Control, + p < 0.05 versus ANP. ANP, Acute Necrotizing Pancreatitis. PEG35, Polyethylene glycol 35. Each determination was carried out in triplicate.