Figure 6.
The effect of EA on PWTs and PWLs (Mean ± SD, n = 6). Rats in SNI-EA, SNI-EA-Con-Lev, or SNI-EA-Syt1-Lev groups were treated with EA at day 8, 10, 12, 14, 16, 18, and 20, for 7 times in total. Rats in the SNI-EA-Syt1-Lev or SNI-EA-Con-Lev groups were intrathecally injected with 15 µL of Syt-1 lentiviral activation particles or lentiviral control particles. The SNI-EA group showed increased ipsilateral PWTs, PWLs (0, 43, and 46 °C) at day 8 to 20 and PWL (49 °C) at day 20 compared with the SNI group. EA induced an increase in ipsilateral PWTs and PWLs at (0, 43, and 46 °C) at day 14 and 20 and in PWL (49 °C) at day 20, which was reversed by the intrathecal administration of Syt-1 lentiviral activation particles. Values with different letters (a, b, and c) on the same day show different (p < 0.05); two-way ANOVA followed by a Bonferroni test.