Table 1.
Bodyweight gain in rats orally exposed to DEHP, DBP, BPA, and their mixture (MIX) for 28 days
| Group | Parameter | 1st Week | 2nd Week | 3rd Week | 4th Week |
|---|---|---|---|---|---|
| Oil Control | BWG | 0.4344 ± 0.05996 | 0.8265 ± 0.1092 | 1.151 ± 0.1708 | 1.425 ± 0.2461 |
| DEHP | BWG | 0.3496 ± 0.02875 * | 0.7347 ± 0.09337 | 1.077 ± 0.1378 | 1.327 ± 0.2461 |
| % to control | −20% | −11% | −6% | −7% | |
| DBP | BWG | 0.2826 ± 0.05433 *** | 0.5559 ± 0.05379 *** | 0.8089 ± 0.06926 *** | 1.016 ± 0.08851 *** |
| % to control | −35% | −33% | −30% | −29% | |
| BPA | BWG | 0.3228 ± 0.03756 *** | 0.7001 ± 0.09798 * | 0.9503 ± 0.1422 * | 1.192 ± 0.1682 * |
| % to control | −26% | −15% | −17% | −16% | |
| MIX | BWG | 0.3190 ± 0.03681 *** | 0.6459 ± 0.04416 ** | 0.9237 ± 0.3505 ** | 1.147 ± 0.1048 ** |
| % to control | −26% | −22% | −20% | −19% |
* p < 0.05, ** p < 0.01; *** p < 0.001. One-way ANOVA with LSD post-hoc test/Kruskal–Wallis test with Dunn’s post-hoc test. Values are presented as the means ± SD (n = 6). BWG: Body weight gain, DEHP: Bis (2-ethylhexyl) phthalate (50 mg/kg b.w.), DBP: Dibutyl phthalate (50 mg/kg b.w.), BPA: Bisphenol A (25 mg/kg b.w.), MIX: Mixture (50 mg/kg b.w. DEHP + 50 mg/kg b.w DBP + 25 mg/kg b.w BPA).