Skip to main content
. 2020 Jan 23;17(3):746. doi: 10.3390/ijerph17030746

Table 4.

Relative organ weights (ROW) of rats orally exposed to DEHP, DBP, BPA, and their mixture (MIX) for 28 days.

Group Parameter Liver Lungs Heart Kidneys Testes Spleen Thymus Brain Thyroid Gland
Oil Control ROW 3.448 ± 0.3311 0.3917 ± 0.04355 0.2833 ± 0.03266 0.6067 ± 0.03615 0.8117 ± 0.1137 0.2000 ± 0.02098 0.1967 ± 0.03011 0.4950 ± 0.05822 0.02600 ± 0.003847
DEHP ROW 4.266 ± 0.2100 *** 0.3560 ± 0.0251 0.3160 ± 0.02302 * 0.6500 ± 0.05701 0.7880 ± 0.1011 0.1800 ± 0.02915 0.2260 ± 0.04615 0.4940 ± 0.03578 0.02400 ± 0.002236
% to control 24 −9 12 7 −3 −10 15 0 −8
DBP ROW 3.560 ± 0.2754 ‡‡ 0.3440 ± 0.05413 0.3160 ± 0.02302 0.600 ± 0.01414 ‡‡ 0.7860 ± 0.08264 0.1920 ± 0.03564 0.1720 ± 0.01483 0.4580 ± 0.01643 0.02250 ± 0.001915
% to control 3 −12 12 −1 −3 −4 −13 −7 −13
BPA ROW 3.390 ± 0.1920 ‡‡‡ 0.3480 ± 0.04147 0.2720 ± 0.02588 0.6040 ± 0.03782 0.8120 ± 0.07120 0.1860 ± 0.03362 0.1680 ± 0.02387 0.4660 ± 0.03050 0.02260 ± 0.001517 *
% to control −2 −11 −4 0 0 −7 −15 −6 −17
MIX ROW 4.032 ± 0.2513 ** 0.4167 ± 0.03327 0.3017 ± 0.01602 0.6783 ± 0.05981 * 0.8467 ± 0.08937 0.1550 ± 0.01517 ** 0.1767 ± 0.03445 0.5183 ± 0.03656 0.02467 ± 0.001862
% to control 17 6 6 12 4 −23 −10 5 −5

* p < 0.05, ** p < 0.01, *** p < 0.001 (compared to the control), p < 0.05, ‡‡ p < 0.01, ‡‡‡ p < 0.001 (compared to the MIX group). One-way ANOVA with LSD post-hoc test/Kruskal–Wallis test with Dunn’s post-hoc test values are presented as the means ± SD (n = 6). ROW: Relative organ weight, DEHP: Bis (2-ethylhexyl) phthalate (50 mg/kg b.w.), DBP: Dibutyl phthalate (50 mg/kg b.w.), BPA: Bisphenol A (25 mg/kg b.w.), MIX: Mixture (50 mg/kg b.w. DEHP + 50 mg/kg b.w DBP + 25 mg/kg b.w BPA).