Table 4.
Group | Parameter | Liver | Lungs | Heart | Kidneys | Testes | Spleen | Thymus | Brain | Thyroid Gland |
---|---|---|---|---|---|---|---|---|---|---|
Oil Control | ROW | 3.448 ± 0.3311 | 0.3917 ± 0.04355 | 0.2833 ± 0.03266 | 0.6067 ± 0.03615 | 0.8117 ± 0.1137 | 0.2000 ± 0.02098 | 0.1967 ± 0.03011 | 0.4950 ± 0.05822 | 0.02600 ± 0.003847 |
DEHP | ROW | 4.266 ± 0.2100 *** | 0.3560 ± 0.0251 | 0.3160 ± 0.02302 * | 0.6500 ± 0.05701 | 0.7880 ± 0.1011 | 0.1800 ± 0.02915 | 0.2260 ± 0.04615‡ | 0.4940 ± 0.03578 | 0.02400 ± 0.002236 |
% to control | 24 | −9 | 12 | 7 | −3 | −10 | 15 | 0 | −8 | |
DBP | ROW | 3.560 ± 0.2754 ‡‡ | 0.3440 ± 0.05413 | 0.3160 ± 0.02302 | 0.600 ± 0.01414 ‡‡ | 0.7860 ± 0.08264 | 0.1920 ± 0.03564 ‡ | 0.1720 ± 0.01483 | 0.4580 ± 0.01643 ‡ | 0.02250 ± 0.001915 |
% to control | 3 | −12 | 12 | −1 | −3 | −4 | −13 | −7 | −13 | |
BPA | ROW | 3.390 ± 0.1920 ‡‡‡ | 0.3480 ± 0.04147 | 0.2720 ± 0.02588 | 0.6040 ± 0.03782‡ | 0.8120 ± 0.07120 | 0.1860 ± 0.03362 | 0.1680 ± 0.02387 | 0.4660 ± 0.03050 | 0.02260 ± 0.001517 * |
% to control | −2 | −11 | −4 | 0 | 0 | −7 | −15 | −6 | −17 | |
MIX | ROW | 4.032 ± 0.2513 ** | 0.4167 ± 0.03327 | 0.3017 ± 0.01602 | 0.6783 ± 0.05981 * | 0.8467 ± 0.08937 | 0.1550 ± 0.01517 ** | 0.1767 ± 0.03445 | 0.5183 ± 0.03656 | 0.02467 ± 0.001862 |
% to control | 17 | 6 | 6 | 12 | 4 | −23 | −10 | 5 | −5 |
* p < 0.05, ** p < 0.01, *** p < 0.001 (compared to the control), ‡ p < 0.05, ‡‡ p < 0.01, ‡‡‡ p < 0.001 (compared to the MIX group). One-way ANOVA with LSD post-hoc test/Kruskal–Wallis test with Dunn’s post-hoc test values are presented as the means ± SD (n = 6). ROW: Relative organ weight, DEHP: Bis (2-ethylhexyl) phthalate (50 mg/kg b.w.), DBP: Dibutyl phthalate (50 mg/kg b.w.), BPA: Bisphenol A (25 mg/kg b.w.), MIX: Mixture (50 mg/kg b.w. DEHP + 50 mg/kg b.w DBP + 25 mg/kg b.w BPA).