Table 1.

Relative Population Doubling (RPD) on TK6 cells after 26 h treatment with STS-135, 5F-AKB-48, APINAC, JWH-018-Cl, JWH-018, and BB-22 at the indicated concentrations with respect to the untreated control [C (-)]. Data are presented as mean ± SEM of five independent experiments.

STS-135	RPD	5F-AKB-48	RPD	APINAC	RPD
C (-)	100.0%	C (-)	100.0%	C (-)	100.0%
12.5 µM	82.1% ± 0.1	12.5 µM	84.1% ± 0.3	12.5 µM	83.2% ± 0.1
25 µM	68.6% ± 0.2	25 µM	81.7% ± 0.1	25 µM	81.2% ± 0.3
35 µM	71.6% ± 0.1	35 µM	80.6% ± 0.2	35 µM	72.6% ± 0.3
50 µM	66.0% ± 0.3	50 µM	70.0% ± 0.2	50 µM	52.2% ± 0.2
75 µM	62.3% ± 0.2	75 µM	61.4% ± 0.1	75 µM	35.7% ± 0.4
JWH-018-Cl	RPD	JWH-018	RPD	BB-22	RPD
C (-)	100.0%	C (-)	100.0%	C (-)	100.0%
12.5 µM	95.9% ± 0.2	12.5 µM	90.1% ± 0.1	12.5 µM	82.4% ± 0.2
25 µM	94.4% ± 0.2	25 µM	89.4% ± 0.4	25 µM	78.8% ± 0.3
35 µM	86.1% ± 0.3	35 µM	75.5% ± 0.3	35 µM	81.1% ± 0.1
50 µM	88.2% ± 0.3	50 µM	82.4% ± 0.1	50 µM	86.4% ± 0.4
75 µM	81.6% ± 0.3	75 µM	75.5% ± 0.3	75 µM	79.8% ± 0.2